Antibody-drug Conjugates Poised To Have Major Impact On Breast Cancer Treatment
Antibody-drug conjugates (ADCs) are rapidly becoming one of the more important therapeutics in targeted cancer treatment. …
Oncology News
Dr. Alan Stolier, MD, FACS, clinical breast oncologist, shares his expert medical perspective with a series of educational and scientific articles.
THE MOST MUTATED GENE WHEN CONSIDERING ALL CANCERS IS TP53. IS IT EQUALLY IMPORTANT IN BREAST CANCER?
TP53 mutations were associated with aggressive histologic features that included high nuclear and histologic grade as well as high Ki67….
Do Hot Flashes During Anti-Estrogen Therapy Impact Breast Cancer Prognosis?
Most breast cancers are estrogen receptor-positive (ER+), approximately 70-80%. There is little doubt that HOT FLASHES are the most common adverse effect….
Is Hormone Replacement Safe After Breast Cancer? Maybe Not.
Arguments have persisted for many years regarding the safety of using hormone replacement during or after the treatment for early-stage (stage I or II) breast cancer. …
Do Breast Cancers With A Low Level Of Estrogen Receptors Behave More Like The More Aggressive Triple-negative Cancers?
Researchers suggest that there may be some important and meaningful clinical activity using a new class of drugs and ER-low cancers….
Does progesterone assist breast cancer cells evade the immune system?
The link between hormones and breast cancer growth has been known for many years and is led to the development of many therapies which have saved countless lives. …
Incidence of implant-associated lymphoma from textured Implants may be higher than expected
In 1997 the first case of a T-cell lymphoma associated with the implant around a silicone capsule was first described by JA Keech and BJ Creech in the Journal of Plastic and Reconstructive Surgery. …
Can Targeted Biologic Treatments Be Used Without Chemotherapy In Her2+ Cancers? Well, Yes And No.
Those patients who had a complete pathological response (no tumor present after anti-HER2 or chemotherapy or both before surgery) had an excellent outcome even without chemotherapy. …
Should we continue to perform sentinel node biopsy in older-aged women?
With the great strides in tumor biology, we appear to be at a precipice where the requirement for any axillary surgery in specific subsets of women will be unnecessary….
Breast Cancer Can And Does Recur After 10 Years
Slightly over half of women with early-stage breast cancer remain disease-free for at least ten years. Unfortunately, recurrences continue beyond the ten-year mark….