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Oncology News

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Dr. Alan Stolier, MD, FACS, clinical breast oncologist, shares his expert medical perspective with a series of educational and scientific articles.

The Likelihood Of Breast Cancer Development In BRCA Women Beyond Age 60

The question remains whether the risk of breast cancer in BRCA1/BRCA2 mutation carriers beyond age 60 is enough to justify intensive screening or prophylactic surgery. …

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Estrogen Receptor Status Breast Cancer screening

The Risk Of A Second Primary Breast Cancer Related To Estrogen Receptor Status

After a woman has developed an initial primary breast cancer, the risk of a second breast cancer takes on greater importance as it relates to surveillance and having the potential to impact the initial primary surgical approach. …

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Older Woman considering prophylactic surgery

Should Older Women Be Tested For BRCA Mutation: Should They Have Prophylactic Surgery?

Most genetic testing and preventive measures are carried out in women less than 50 years. A multinational, multi-institutional group of scientists studied BRCA1 and BRCA2-positive patients from ages 50 to 75 to estimate the cumulative risk of all cancers. …

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Scientists Suggest That Extrachromosomal DNA Could Eventually Transform Cancer Treatment

Current guidelines recommend only clinician visits to detect breast cancer recurrence following initial treatment. Imaging is only recommended for those patients demonstrating signs or symptoms of recurrence….

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SURVEILLANCE AFTER STAGE II – III BREAST CANCER imaging graphic

Surveillance After Stage II – III Breast Cancer: Routine Vs. Symptomatic Imaging

Current guidelines recommend only clinician visits to detect breast cancer recurrence following initial treatment. Imaging is only recommended for those patients demonstrating signs or symptoms of recurrence….

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Oncology antibody article graphic

Antibody-drug Conjugates Poised To Have Major Impact On Breast Cancer Treatment

Antibody-drug conjugates (ADCs) are rapidly becoming one of the more important therapeutics in targeted cancer treatment. …

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Mutated gene rendering

THE MOST MUTATED GENE WHEN CONSIDERING ALL CANCERS IS TP53. IS IT EQUALLY IMPORTANT IN BREAST CANCER?

TP53 mutations were associated with aggressive histologic features that included high nuclear and histologic grade as well as high Ki67….

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Do Hot Flashes During Anti-Estrogen Therapy Impact Breast Cancer Prognosis?

Most breast cancers are estrogen receptor-positive (ER+), approximately 70-80%. There is little doubt that HOT FLASHES are the most common adverse effect….

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Is Hormone Replacement Safe After Breast Cancer? Maybe Not.

Arguments have persisted for many years regarding the safety of using hormone replacement during or after the treatment for early-stage (stage I or II) breast cancer. …

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Femail patient looking at medication provided by nurse

Do Breast Cancers With A Low Level Of Estrogen Receptors Behave More Like The More Aggressive Triple-negative Cancers?

Researchers suggest that there may be some important and meaningful clinical activity using a new class of drugs and ER-low cancers….

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